前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體
Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9
- 編號UMAE189Ra21
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C5
- Ig亞型 IgG2b Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPE189Ra01-前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/ml
- 且適物種Homo sapiens (Human，人)
- 應(yīng)用WB; IHC
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 360 ¥ 840 ¥ 1200 ¥ 3000 ¥ 12000
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Samples: Rat Stomach Tissue; Primary Ab: 10ug/ml Mouse Anti-Rat PCSK9 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Samples: Rat Kidney Tissue;
Primary Ab: 10ug/ml Mouse Anti-Rat PCSK9 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19) -
DAB staining on IHC-P;
Samples: Rat Cerebrum Tissue;
Primary Ab: 10ug/ml Mouse Anti-Rat PCSK9 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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Western Blot; Sample: Human Jurkat cell lysate; <br/>Primary Ab: 3μg/ml Mouse Anti-Rat PCSK9 Antibody<br/>Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody<br/>(Catalog: SAA544Mu19)
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Western Blot; Sample: Human A431 cell lysate;
Primary Ab: 3μg/ml Mouse Anti-Rat PCSK9 Antibody
Second Ab: 0.2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對PCSK9的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別PCSK9。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)多克隆抗體 | WB,IHC,ICC/IF |
| UMAE189Ra23 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | IHC |
| UMAE189Ra22 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB |
| UMAE189Ra21 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC |
| UFAE189Ra02 | 抗前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | FCM |
| USEE189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULME189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Biological Trace Element Research | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers [pubmed:28409410] |
| BASIC RESEARCH IN CARDIOLOGY | Autocrine effects of PCSK9 on cardiomyocytes [Pubmed: 33169229] |
| J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans [33407555] |
| Metabolism | MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice [33775647] |
| Eur Rev Med Pharmacol Sci | Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders [34533801] |
| Clin Exp Hypertens | Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease [Pubmed:35502687] |
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