胰島素降解酶(IDE)重組蛋白
Recombinant Insulin Degrading Enzyme (IDE)
Insulysin; Insulin Protease; Abeta-degrading protease; Insulinase
- 編號URPB897Mu01
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞膜, 分泌
- 預(yù)測分子量29.7kDa
- 實(shí)際分子量30kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ala753~Pro973 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)6.4
-
應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 612 ¥ 1530 ¥ 3060 ¥ 9180 ¥ 22950
- 欲了解實(shí)際交易價格和更多情況，請與當(dāng)?shù)亟?jīng)銷商聯(lián)系!
-
產(chǎn)品包裝(模擬)
-
產(chǎn)品包裝(模擬)
-
Figure. SDS-PAGE
-
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPB897Mu02 | 胰島素降解酶(IDE)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPB897Mu01 | 胰島素降解酶(IDE)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB897Mu02 | 胰島素降解酶(IDE)多克隆抗體 | WB; IHC |
| UPAB897Mu01 | 胰島素降解酶(IDE)多克隆抗體 | WB; IHC |
| USEB897Mu | 胰島素降解酶(IDE)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB897Mu | 胰島素降解酶(IDE)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| J Neurochem | Reduction [PubMed: 26442993] |
| African Journal of Pharmacy and Pharmacology | Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats [article-full-text-pdf] |
| Biomedicine & Pharmacotherapy | Vitamin?D3?intake?as?regulator?of?insulin?degrading?enzyme?and?insulin?receptor?phosphorylationin?diabetic?rats. [pubmed:27930980] |
| Biological Trace Element Research | Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats [10.1007/s12011-017-1167-z] |
| Neuroscience | The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A [Pubmed:29406271] |
留言咨詢
