半乳糖凝集素9(GAL9)重組蛋白
Recombinant Galectin 9 (GAL9)
LGALS9; Ecalectin; Lectin,Galactoside-Binding Soluble 9; Tumor antigen HOM-HD-21
- 編號(hào)URPA309Ca01
- 物種Canis familiaris; Canine (Dog，犬) 相同的名稱(chēng)，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌
- 預(yù)測(cè)分子量51.7kDa
- 實(shí)際分子量53kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Phe17~Thr355 with Two N-terminal Tags, His-tag and SUMO-tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)9.2
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 600 ¥ 1500 ¥ 3000 ¥ 9000 ¥ 22500
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Canis familiaris; Canine (Dog，犬) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA309Ca01 | 半乳糖凝集素9(GAL9)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA309Ca01 | 半乳糖凝集素9(GAL9)多克隆抗體 | WB |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| American Journal of Nephrology | Temporal Increases in Urinary Carboxymethyllysine Correlate with Albuminuria Development in Diabetes [Karger: 328581] |
| Clinical Immunology | Galectin-9 administration ameliorates CVB3 induced myocarditis by promoting the proliferation of regulatory T cells and alternatively activated Th2 cells [ScienceDirect: S1521661611001057] |
| Renal Failure | Rat Renal Interstitial Fibroblasts Affect the Th1/Th2 Profile In Vitro [Pubmed: 22013937] |
| BMC Nephrol | Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease [PubMed: 23339460] |
| Retrovirology | Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection [PubMed: PMC3750478] |
| PLoS One. | Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection [PubMed: PMC3480425] |
| PLoS Pathogens | Galectin-9 and IL-21 Mediate Cross-regulation between Th17 and Treg Cells during Acute Hepatitis C [PubMed: PMC3688567] |
| PLOS ONE | Graves’ Disease Is Associated with a Defective Expression of the Immune Regulatory Molecule Galectin-9 in Antigen-Presenting Dendritic Cells [PubMed: 25880730] |
| Advances in Experimental?Medicine?and?Biology | Molecules of Damage-Associated Patterns in Bronchoalveolar Lavage Fluid and Serum in Chronic Obstructive Pulmonary Disease [Pubmed:29429028] |
| Journal?of?Microbiology,?Immunology?and?Infection | Galectin-9-like from Angiostrongylus cantonensis young adult worms modulates eosinophil chemotaxis in vitro [Doi: 10.1016/j.jmii.2018.09.010] |
| Oncology?Letters | The effects of Tim?3 activation on T?cells in gastric cancer progression [] |
| Scientific Reports | Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra?… [Pubmed: 31337865] |
| Biomolecules | Blood Levels of Galectin-9, an Immuno-Regulating Molecule, Reflects the Severity for the Acute and Chronic Infectious Diseases. Biomolecules 2021, 11, 430 [33804076] |
| Medicine | Regulatory T cells, damage-associated molecular patterns, and myeloid-derived suppressor cells in bronchoalveolar lavage fluid interlinked with chronic obstructive?… [Pubmed:35687771] |
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