組織蛋白酶D(CTSD)重組蛋白
Recombinant Cathepsin D (CTSD)
CPSD; CLN10; Lysosomal Aspartyl Protease; Ceroid-Lipofuscinosis,Neuronal 10
- 編號URPB280Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌, 溶酶體, 細胞外基質(zhì)
- 預測分子量13.5kDa
- 實際分子量15kDa(差異分析請參閱說明書)
- 片段與標簽Lys54~Asp163 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 95%
- 等電點6.9
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 744 ¥ 1860 ¥ 3720 ¥ 11160 ¥ 27900
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPB280Ra01 | 組織蛋白酶D(CTSD)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPB280Ra03 | 組織蛋白酶D(CTSD)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPB280Ra02 | 組織蛋白酶D(CTSD)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB280Ra03 | 組織蛋白酶D(CTSD)多克隆抗體 | WB; IHC |
| UPAB280Ra02 | 組織蛋白酶D(CTSD)多克隆抗體 | IHC |
| UPAB280Ra01 | 組織蛋白酶D(CTSD)多克隆抗體 | WB,IHC,ICC/IF |
| UFAB280Ra01 | 抗組織蛋白酶D(CTSD)多克隆抗體 | FCM |
| USEB280Ra | 組織蛋白酶D(CTSD)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB280Ra | 組織蛋白酶D(CTSD)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Molecular Immunology | Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro [ScienceDirect: S0161589011008297] |
| 21 | Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation [PubMed: 25732418] |
| Scientific Reportes | Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention [pubmed:27922112] |
| Biomedicine & pharmacotherapy | Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms [pubmed:28061403] |
| JGH OPEN | Limited applicability of cathepsin D for the diagnosis and monitoring of non‐alcoholic steatohepatitis [] |
| Diabetologia | Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans [Pubmed: 31690989] |
| Antioxidants | Iron and Advanced Glycation End Products: Emerging Role of Iron in Androgen Deficiency in Obesity [Pubmed: 32235809] |
| Peptides | LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders [33253777] |
| Cells | Identification of Cathepsin D as a Plasma Biomarker for Alzheimer's Disease [33445607] |
| J Chem Neuroanat | Analysis of silymarin-modulating effects against acrylamide-induced cerebellar damage in male rats: Biochemical and pathological markers [33965515] |
| Front Cell Infect Microbiol | PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence [33042856] |
| Nutr Metab Cardiovasc Dis | Serum CathepsinD in pregnancy: relation with metabolic and inflammatory markers and effects of fish oils and probiotics [Pubmed:35304048] |
| Biosensors | A Comparison of Various Chips Used for the Manufacture of Biosensors Applied in Non-Fluidic Array SPRi, Based on the Example of Determination of Cathepsin D [Pubmed:35049649] |
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