顆粒酶B(GZMB)單克隆抗體
Monoclonal Antibody to Granzyme B (GZMB)
GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B
- 編號UMAA600Hu22
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)D2
- Ig亞型 IgG2b Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPA600Hu01-顆粒酶B(GZMB)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用WB
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 302 ¥ 706 ¥ 1008 ¥ 2520 ¥ 10080
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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IHC圖
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Western Blot; Sample: Human PBMC cell lysate Primary Ab: 0.04μg/ml Mouse Anti-Human GZMB Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對GZMB的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別GZMB。
用法
Western blotting: 0.01-2μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA600Hu01 | 顆粒酶B(GZMB)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA600Hu01 | 顆粒酶B(GZMB)多克隆抗體 | WB; IHC |
| UMAA600Hu22 | 顆粒酶B(GZMB)單克隆抗體 | WB |
| UMAA600Hu21 | 顆粒酶B(GZMB)單克隆抗體 | WB |
| USEA600Hu | 顆粒酶B(GZMB)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA600Hu | 顆粒酶B(GZMB)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| International Journal of Cancer | Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70 [Pubmed:24691976] |
| Biol Pharm Bull. | Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 Melanoma [Pubmed:24818259] |
| Journal of Dermatological Science | Relationships?among?plasma?granzyme?B?level,?pruritus?and?dermatitis?in?patients?with?atopicdermatitis. [pubmed:27686401] |
| Oncotarget | Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment [Pubmed:29983866] |
| Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors [Pubmed: 31695790] |
| Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma [34377237] |
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