轉(zhuǎn)化生長因子β1(TGFb1)活性蛋白
Active Transforming Growth Factor Beta 1 (TGFb1)
TGF-B1; CED; DPD1; LAP; Camurati-Engelmann Disease; Latency-associated peptide
- 編號UAPA124Hu63
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 緩沖液成份PBS, pH7.4, containing 5% Trehalose.
- 性狀凍干粉
- 純度> 80%
- 等電點8.4
- 應用Cell?culture;?Activity?Assays.
- 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 696 ¥ 1740 ¥ 3480 ¥ 10440 ¥ 26100
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認證
活性實驗
Transforming Growth Factor Beta 1 (TGFB1) belongs to TGF-beta family. As a secreted protein and a cytokine, TGFB plays a role in the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function. Besides, TGFB1 regulates cell proliferation, differentiation, adhesion, migration by transducing the signal through transmembrane receptors type I and type II (TGFBR1 and TGFBR2). To test the effect of TGFb1 on inhibit IL4-dependent proliferation, CTLL-2 cells were seeded into triplicate wells of 96-well plates, the medium was 2% serum RPMI-1640?including various concentrations of recombinant human TGFb1. After incubated for 72h,?cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10 μl of CCK-8 solution was added to each well of the plate, then the absorbance at 450 nm was measured. Cell viability was assessed by CCK-8 assay. The result was shown in Figure1. It was obvious that TGFB1 significantly decreased cell viability of CTLL-2 cells. The ED50 of recombinant human TGFB1 is 2.91μg/mL.
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| URPA124Hu02 | 轉(zhuǎn)化生長因子β1(TGFb1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu64 | 轉(zhuǎn)化生長因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu63 | 轉(zhuǎn)化生長因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu65 | 轉(zhuǎn)化生長因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA124Hu01 | 轉(zhuǎn)化生長因子β1(TGFb1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPA124Hu63 | 轉(zhuǎn)化生長因子β1(TGFb1)活性蛋白 | Cell?culture;?Activity?Assays. |
| UAPA124Hu01 | 轉(zhuǎn)化生長因子β1(TGFb1)活性蛋白 | Cell?culture;?Activity?Assays. |
| UEPA124Hu62 | 轉(zhuǎn)化生長因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu61 | 轉(zhuǎn)化生長因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA124Hu01 | 轉(zhuǎn)化生長因子β1(TGFb1)多克隆抗體 | IHC |
| ULAA124Hu71 | 轉(zhuǎn)化生長因子β1(TGFb1)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| ULAA124Hu81 | 轉(zhuǎn)化生長因子β1(TGFb1)多克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| UMAA124Hu23 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu24 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu25 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | WB; IHC |
| URAA124Hu21 | 轉(zhuǎn)化生長因子β1(TGFb1)重組抗體 | WB; IF; ICC; IHC; IP; FCM. |
| UMAA124Hu27 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | WB |
| UMAA124Hu29 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu21 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu26 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu28 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu22 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | WB |
| UFAA124Hu02 | 抗轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體 | FCM |
| ULAA124Hu82 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| ULAA124Hu72 | 轉(zhuǎn)化生長因子β1(TGFb1)單克隆抗體(生物素標記) | WB; IHC; ICC. |
| UMEA124Hu | 轉(zhuǎn)化生長因子β1(TGFb1)檢測試劑盒(酶聯(lián)免疫吸附試驗法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USEA124Hu | 轉(zhuǎn)化生長因子β1(TGFb1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA124Hu | 轉(zhuǎn)化生長因子β1(TGFb1)檢測試劑盒(化學發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA124Hu | 轉(zhuǎn)化生長因子β1(TGFb1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UPSA124Hu01 | 轉(zhuǎn)化生長因子β1(TGFb1)抗體對 | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| UKSA124Hu01 | 轉(zhuǎn)化生長因子β1(TGFb1)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
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| Biomed Pharmacother | Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma [Pubmed: 32036215] |
| Biochemical and Biophysical Research Communications | Isorhynchophylline exerts anti-asthma effects in mice by inhibiting the proliferation of airway smooth muscle cells: The involvement of miR-200a-mediated FOXC1/NF?… [Pubmed: 31733831] |
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Vitamin D Attenuates Loss of Endothelial Biomarker Expression in Cardio-Endothelial Cells [Pubmed: 32235811] |
| Journal of Oral Biology and Craniofacial Research | Levels of TGF-β1 in peri-miniscrew implant crevicular fluid [Pubmed: 32211284] |
| Acta Histochem | Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway [Pubmed: 33166863] |
| EUROPEAN JOURNAL OF PHARMACOLOGY | The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation [Pubmed: 33122672] |
| Journal of Cosmetic Dermatology | Examination of androgenetic alopecia with serum biomarkers [Pubmed: 32969583] |
| MOLECULAR AND CELLULAR BIOCHEMISTRY | Soluble recombinant human thrombomodulin suppresses inflammation-induced gastrointestinal tumor growth in a murine peritonitis model [Pubmed: 32767229] |
| CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | Hepatoprotective effect of Linagliptin against liver fibrosis induced by carbon tetrachloride in mice [Pubmed: 32726558] |
| EXPERIMENTAL DERMATOLOGY | Decreased suppression of CD8+ and CD4+ T cells by peripheral Regulatory T cells in Generalized Vitiligo due to reduced NFATC1 and FOXP3 proteins [Pubmed: 32682346] |
| Scientific Reports | Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways [Pubmed: 32661331] |
| international journal of biological macromolecules | Chlorella vulgaris α-L-arabino-α-L-rhamno-α, β-D-galactan structure and mechanisms of its anti-inflammatory and anti-remodelling effects [Pubmed: 32565301] |
| Exp Cell Res | Exosomal miR-532–5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5 [Pubmed: 32464126] |
| JOURNAL OF IMMUNOLOGY RESEARCH | The Sufficient Immunoregulatory Effect of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation on Regulatory T Cells in Patients with … [Pubmed: 32411794] |
| Frontiers in Pharmacology | M10, a Myricetin-3-ObD-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice [Pubmed: 33041798] |
| Food & Function | Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?… [] |
| Effect of metformin and indole-3-carbinol on a rat model of Parkinson's disease induced by 6-hydroxydopamine [] | |
| Research square | Vitamin D Status in Dupuytren's Disease: Association with Clinical Status and Vitamin D Receptor Expression [] |
| Phytomedicine | Menthacarin attenuates experimental colitis [] |
| Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study [] | |
| BMC Complement Med Ther | Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma [33413331] |
| Life Sci | Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats [33577848] |
| CLINICAL SCIENCE | Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes [33491733] |
| Bioact Mater | New design to remove leukocytes from platelet-rich plasma (PRP) based on cell dimension rather than density [33842739] |
| Acta Biomater | Highly interconnected inverse opal extracellular matrix scaffolds enhance stem cell therapy in limb ischemia [33878473] |
| Mol Cell Biochem | Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in??- [33864569] |
| Cell Death & Disease | Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization [34006822] |
| PLoS One | Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment?aIn vivo studies [33999928] |
| Vascular pharmacology | Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4-LYVE1 axis [33945869] |
| Equine Vet J | Limited added value of negative pressure wound therapy compared to calcium alginate dressings for second intention healing in a non?\contaminated and??- [34115409] |
| Stem Cells International | The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin??- [33381190] |
| Journal of Pharmacy and Pharmacology | Pharmacodynamic evaluation of dihydroxyflavone derivate chrysin in a guinea pig model of allergic asthma [33793800] |
| Bull. Egypt. Soc. Physiol. Sci. | Flaxseed Oil Supplementation Afford Comparable Therapeutic effect to Metformin in Bleomycin Induced Pulmonary Fibrosis Rat model [] |
| D￡?ˉ | Role of Angiotensin II and Renal Nerves on TGF-b/SmadPathway in Diabetic Nephropathy Rat Model [] |
| Bioactive Materials | Calcium phosphate-based materials regulate osteoclast-mediated osseointegration [] |
| Mediators of Inflammation | Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of |á1, 3 ?- [] |
| Manuscript title Microparticles Containing MiR-625-5p In Coronary Artery Reduce Myocardial Fibrosis After Myocardial Infarction [] | |
| Andrology | X‐ray micro‐computed tomography in the assessment of penile cavernous fibrosis in a rabbit castration model [34236146] |
| Aging | Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular?… [34315133] |
| Tissue Eng Regen Med | Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method [34339025] |
| Am J Transl Res | Wuling San and Xiao Chaihu Decoction affect airway inflammatory response and airway smooth muscle cell proliferation in mice with allergic asthma via miR?… [34786062] |
| Biomacromolecules | In Situ Forming Cellulose Nanofibril-Reinforced Hyaluronic Acid Hydrogel for Cartilage Regeneration [34723499] |
| Brain Sci | Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial?… [34942919] |
| Biomedicines | Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes [34829910] |
| J Inflamm Res | Clenbuterol, a Selective β2-Adrenergic Receptor Agonist, Inhibits or Limits Post-Stroke Pneumonia, but Increases Infarct Volume in MCAO Mice [Pubmed:35058704] |
| Cancer Commun (Lond) | Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancer [Pubmed:34981670] |
| Polymers (Basel) | 3D Printed Scaffold Based on Type I Collagen/PLGA_TGF-β1 Nanoparticles Mimicking the Growth Factor Footprint of Human Bone Tissue [Pubmed:35267680] |
| Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007] |
| Biomed Pharmacother | Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats [Pubmed:35430394] |
| Antioxidants | Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant's Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory?… [Pubmed:35204215] |
| Frontiers in Molecular Neuroscience | Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines [Pubmed:35465093] |
| Vaccines | Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated?… [Pubmed:35632433] |
| Biomaterials Advances | Human adipose-derived stem cell-loaded small intestinal submucosa as a bioactive wound dressing for the treatment of diabetic wounds in rats [] |
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